An exploratory study of the association between KCNB1 rs1051295 and type 2 diabetes and its related traits in Chinese Han population.

An exploratory study of the association between KCNB1 rs1051295 and type 2 diabetes and its related traits in Chinese Han population.

Since the KCNB1 encoding Kv2.1 channel accounts for the majority of Kv currents modulating insulin secretion by pancreatic islet beta-cells, we postulated that KCNB1 is a plausible candidate gene for genetic variation contributing to the variable compensatory secretory function of beta-cells in type...

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Bibliographic Details
Main Authors: Yu-Xiang Zhang, Yan Liu, Jing Dong, You-Xin Wang, Jing Wang, Guo-Qing Zhuang, Shu-Jing Han, Qing-Qing Guo, Yan-Xia Luo, Jie Zhang, Xiao-Xia Peng, Ling Zhang, Yu-Xiang Yan, Xing-Hua Yang, Hong Wang, Xu Han, Guang-Xu Liu, You-Hou Kang, You-Qin Liu, Sheng-Feng Weng, Hong Zhang, Xiao-Qiang Zhang, Ke-Bao Jia, Li Wang, Lei Zhao, Zhong-Xin Xiao, Shu-Hua Zhang, Hui-Hui Wu, Qing-Xuan Lai, Na Qi, Wei Wang, Herbert Gaisano, Fen Liu, Yan He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3576392?pdf=render

Internet

http://europepmc.org/articles/PMC3576392?pdf=render

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