Titania Nanosheet Generates Peroxynitrite-Dependent <i>S-</i>Nitrosylation and Enhances p53 Function in Lung Cancer Cells

Metal nanomaterials can enhance the efficacy of current cancer therapies. Here, we show that Ti<sub>0</sub><sub>.8</sub>O<sub>2</sub> nanosheets cause cytotoxicity in several lung cancer cells but not in normal cells. The nanosheet-treated cells showed certain apo...

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Bibliographic Details
Main Authors: Rapeepun Soonnarong, Sucharat Tungsukruthai, Bodee Nutho, Thanyada Rungrotmongkol, Chanida Vinayanuwattikun, Tosapol Maluangnont, Pithi Chanvorachote
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
p53
Online Access:https://www.mdpi.com/1999-4923/13/8/1233