Inactivation of Heparin by Cationically Modified Chitosan

Inactivation of Heparin by Cationically Modified Chitosan

This study was performed to evaluate the ability of N-(2-hydroxypropyl)-3-tri methylammonium chitosan chloride (HTCC), the cationically modified chitosan, to form biologically inactive complexes with unfractionated heparin and thereby blocking its anticoagulant activity. Experiments were carried out...

Full description

Bibliographic Details
Main Authors: Barbara Lorkowska-Zawicka, Kamil Kamiński, Justyna Ciejka, Krzysztof Szczubiałka, Magdalena Białas, Krzysztof Okoń, Dariusz Adamek, Maria Nowakowska, Jacek Jawień, Rafał Olszanecki, Ryszard Korbut
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Marine Drugs
Subjects:
chitosan
HTCC
unfractionated heparin
heparin antidote
protamine
coagulation
hepatotoxicity
Online Access:http://www.mdpi.com/1660-3397/12/7/3953

Similar Items

Similar Items