Inactivation of Heparin by Cationically Modified Chitosan

Inactivation of Heparin by Cationically Modified Chitosan

This study was performed to evaluate the ability of N-(2-hydroxypropyl)-3-tri methylammonium chitosan chloride (HTCC), the cationically modified chitosan, to form biologically inactive complexes with unfractionated heparin and thereby blocking its anticoagulant activity. Experiments were carried out...

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Bibliographic Details
Main Authors: Barbara Lorkowska-Zawicka, Kamil Kamiński, Justyna Ciejka, Krzysztof Szczubiałka, Magdalena Białas, Krzysztof Okoń, Dariusz Adamek, Maria Nowakowska, Jacek Jawień, Rafał Olszanecki, Ryszard Korbut
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Marine Drugs
Subjects:
chitosan
HTCC
unfractionated heparin
heparin antidote
protamine
coagulation
hepatotoxicity
Online Access:http://www.mdpi.com/1660-3397/12/7/3953

Internet

http://www.mdpi.com/1660-3397/12/7/3953

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