Introduction of Cysteines in the Stalk Domain of Recombinant Influenza Virus N1 Neuraminidase Enhances Protein Stability and Immunogenicity in Mice
Influenza virus surface glycoproteins represent the main targets of the immune system during infection and vaccination. Current influenza virus vaccines rely mostly on the hemagglutinin, requiring a close match between the vaccine and circulating strains. Recently, the neuraminidase (NA) has become...
Main Authors: | Shirin Strohmeier, Juan Manuel Carreño, Ruhi Nichalle Brito, Florian Krammer |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | Vaccines |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-393X/9/4/404 |
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