Association of the 3′UTR FOXO3a Polymorphism rs4946936 with an Increased Risk of Childhood Acute Lymphoblastic Leukemia in a Chinese Population

Association of the 3′UTR FOXO3a Polymorphism rs4946936 with an Increased Risk of Childhood Acute Lymphoblastic Leukemia in a Chinese Population

Background/Aims: FOXO3a is an essential tumor suppressor that regulates the mechanisms of tumorigenesis and leukemogenesis. FOXO3a polymorphisms have not been reported previously associated with an increased risk for childhood acute lymphoblastic leukemia (ALL). In this study, the rs4946936 polymorp...

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Bibliographic Details
Main Authors: Yaping Wang, Li Zhou, Jing Chen, Jie Li, Lulu He, Peng Wu, Meilin Wang, Na Tong, Zhengdong Zhang, Yongjun Fang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
SNP
FOXO3a
Childhood ALL
miR-223
Transfection
Online Access:http://www.karger.com/Article/FullText/363002

Internet

http://www.karger.com/Article/FullText/363002

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