Strategies To Modulate Heritable Epigenetic Defects in Cellular Machinery: Lessons from Nature

Strategies To Modulate Heritable Epigenetic Defects in Cellular Machinery: Lessons from Nature

Natural epigenetic processes precisely orchestrate the intricate gene network by expressing and suppressing genes at the right place and time, thereby playing an essential role in maintaining the cellular homeostasis. Environment-mediated alteration of this natural epigenomic pattern causes abnormal...

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Bibliographic Details
Main Authors: Ganesh N. Pandian, Hiroshi Sugiyama
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Pharmaceuticals
Subjects:
epigenetic inheritance
chemical mimics
HDAC inhibitors
regenerative medicine
cancer treatment
programmable genetic switches
histone code
epigenetic switch based therapy
future medicine
Online Access:http://www.mdpi.com/1424-8247/6/1/1

Internet

http://www.mdpi.com/1424-8247/6/1/1

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