Identifying longevity associated genes by integrating gene expression and curated annotations.

Aging is a complex process with poorly understood genetic mechanisms. Recent studies have sought to classify genes as pro-longevity or anti-longevity using a variety of machine learning algorithms. However, it is not clear which types of features are best for optimizing classification performance an...

Full description

Bibliographic Details
Main Authors: F William Townes, Kareem Carr, Jeffrey W Miller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008429