The Multiple Roles of Peptidyl Prolyl Isomerases in Brain Cancer

The Multiple Roles of Peptidyl Prolyl Isomerases in Brain Cancer

Peptidyl prolyl isomerases (PPIases) are broadly expressed enzymes that accelerate the cis-trans isomerization of proline peptide bonds. The most extensively studied PPIase family member is protein interacting with never in mitosis A1 (PIN1), which isomerizes phosphorylated serine/threonine&ndas...

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Bibliographic Details
Main Author: Stefano Stifani
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Biomolecules
Subjects:
brain cancer
cancer stem-like cells
glioblastoma
medulloblastoma
nuclear factor-kappa B
PIN1
peptidyl prolyl isomerase
Online Access:http://www.mdpi.com/2218-273X/8/4/112

Internet

http://www.mdpi.com/2218-273X/8/4/112

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