The Oxidosqualene Cyclase from the Oomycete Saprolegnia Parasitica Synthesizes Lanosterol as a Single Product

The first committed step of sterol biosynthesis is the cyclisation of 2,3-oxidosqualene to form either lanosterol or cycloartenol. This is catalyzed by an oxidosqualene cyclase. Lanosterol and cycloartenol are subsequently converted into various sterols by a series of enzyme reactions. The specifici...

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Bibliographic Details
Main Authors: Paul Dahlin, Vaibhav Srivastava, Vincent Bulone, Lauren Sara McKee
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01802/full