Investigation of cross-species translatability of pharmacological MRI in awake nonhuman primate - a buprenorphine challenge study.

Investigation of cross-species translatability of pharmacological MRI in awake nonhuman primate - a buprenorphine challenge study.

BACKGROUND: Pharmacological MRI (phMRI) is a neuroimaging technique where drug-induced hemodynamic responses can represent a pharmacodynamic biomarker to delineate underlying biological consequences of drug actions. In most preclinical studies, animals are anesthetized during image acquisition to mi...

Full description

Bibliographic Details
Main Authors: Stephanie Seah, Abu Bakar Ali Asad, Richard Baumgartner, Dai Feng, Donald S Williams, Elaine Manigbas, John D Beaver, Torsten Reese, Brian Henry, Jeffrey L Evelhoch, Chih-Liang Chin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4206294?pdf=render

Internet

http://europepmc.org/articles/PMC4206294?pdf=render

Similar Items