IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates

IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates

Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and requires appropriate adjuvants. We previously demon...

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Bibliographic Details
Main Authors: Sandrine Logerot, Suzanne Figueiredo-Morgado, Bénédicte Charmeteau-de-Muylder, Abdelkader Sandouk, Anne-Sophie Drillet-Dangeard, Morgane Bomsel, Isabelle Bourgault-Villada, Anne Couëdel-Courteille, Rémi Cheynier, Magali Rancez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
mucosal adjuvant
interleukin-7
female genital tract
mucosal immune responses
non-human primates
chemokine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.614115/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.614115/full

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