Marine Invertebrate Xenobiotic-Activated Nuclear Receptors: Their Application as Sensor Elements in High-Throughput Bioassays for Marine Bioactive Compounds

Developing high-throughput assays to screen marine extracts for bioactive compounds presents both conceptual and technical challenges. One major challenge is to develop assays that have well-grounded ecological and evolutionary rationales. In this review we propose that a specific group of ligand-...

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Bibliographic Details
Main Authors: Ingrid Richter, Andrew E. Fidler
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/12/11/5590