Regional sequence expansion or collapse in heterozygous genome assemblies.

Regional sequence expansion or collapse in heterozygous genome assemblies.

High levels of heterozygosity present a unique genome assembly challenge and can adversely impact downstream analyses, yet is common in sequencing datasets obtained from non-model organisms. Here we show that by re-assembling a heterozygous dataset with variant parameters and different assembly algo...

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Bibliographic Details
Main Authors: Kathryn C Asalone, Kara M Ryan, Maryam Yamadi, Annastelle L Cohen, William G Farmer, Deborah J George, Claudia Joppert, Kaitlyn Kim, Madeeha Froze Mughal, Rana Said, Metin Toksoz-Exley, Evgeny Bisk, John R Bracht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008104

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https://doi.org/10.1371/journal.pcbi.1008104

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