<i>Physalis peruviana</i>-Derived Physapruin A (PHA) Inhibits Breast Cancer Cell Proliferation and Induces Oxidative-Stress-Mediated Apoptosis and DNA Damage

<i>Physalis peruviana</i>-Derived Physapruin A (PHA) Inhibits Breast Cancer Cell Proliferation and Induces Oxidative-Stress-Mediated Apoptosis and DNA Damage

Breast cancer expresses clinically heterogeneous characteristics and requires multipurpose drug development for curing the different tumor subtypes. Many withanolides have been isolated from <i>Physalis</i> species showing anticancer effects, but the anticancer function of physapruin A (...

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Bibliographic Details
Main Authors: Tzu-Jung Yu, Yuan-Bin Cheng, Li-Ching Lin, Yi-Hong Tsai, Bo-Yi Yao, Jen-Yang Tang, Fang-Rong Chang, Chia-Hung Yen, Fu Ou-Yang, Hsueh-Wei Chang
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Antioxidants
Subjects:
withanolide
breast cancer
apoptosis
oxidative stress
DNA damage
Online Access:https://www.mdpi.com/2076-3921/10/3/393

Internet

https://www.mdpi.com/2076-3921/10/3/393

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