Potential mechanisms underlying the protective effect of pregnancy against breast cancer: A focus on the IGF pathway
A first full term birth at an early age protects women against breast cancer by reducing lifetime risk by up to 50%. The underlying mechanism resulting in this protective effect remains unclear, but many avenues have been investigated, including lobular differentiation, cell fate, and stromal compos...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2016-10-01
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Series: | Frontiers in Oncology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00228/full |