The synovial fluid neuropeptide PACAP may act as a protective factor during disease progression of primary knee osteoarthritis and is increased following hyaluronic acid injection

The correlation of serum and synovial fluid (SF) pituitary adenylate cyclase-activating polypeptide (PACAP) levels with disease progression of primary knee osteoarthritis (OA) was explored. Radiographic severity of OA was determined by Kellgren–Lawrence (K-L) grades. PACAP levels were measured by EL...

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Bibliographic Details
Main Authors: Zheng-Ping Sun, Shao-Peng Wu, Can-De Liang, Chuan-Xi Zhao, Bing-Yin Sun
Format: Article
Language:English
Published: SAGE Publishing 2019-05-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425919839125