Study protocol: multicenter double-blind, randomized, placebo-controlled trial of rituximab for the treatment of childhood-onset early-stage uncomplicated frequently relapsing or steroid-dependent nephrotic syndrome (JSKDC10 trial)

Study protocol: multicenter double-blind, randomized, placebo-controlled trial of rituximab for the treatment of childhood-onset early-stage uncomplicated frequently relapsing or steroid-dependent nephrotic syndrome (JSKDC10 trial)

Abstract Background Eighty percent of children with idiopathic nephrotic syndrome respond well to steroid therapy, but up to 50% of patients with steroid-sensitive nephrotic syndrome exhibit frequently relapsing (FRNS) or steroid-dependent nephrotic syndrome (SDNS). Several studies identified the ch...

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Bibliographic Details
Main Authors: China Nagano, Mayumi Sako, Koichi Kamei, Kenji Ishikura, Hidefumi Nakamura, Koichi Nakanishi, Takashi Omori, Kandai Nozu, Kazumoto Iijima
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Nephrology
Subjects:
Frequently relapsing nephrotic syndrome
Steroid-sensitive nephrotic syndrome
Rituximab
Online Access:http://link.springer.com/article/10.1186/s12882-019-1470-3

Internet

http://link.springer.com/article/10.1186/s12882-019-1470-3

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