Chemically activated luminopsins allow optogenetic inhibition of distributed nodes in an epileptic network for non-invasive and multi-site suppression of seizure activity

Although optogenetic techniques have proven to be invaluable for manipulating and understanding complex neural dynamics over the past decade, they still face practical and translational challenges in targeting networks involving multiple, large, or difficult-to-illuminate areas of the brain. We util...

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Bibliographic Details
Main Authors: Jack K. Tung, Fu Hung Shiu, Kevin Ding, Robert E. Gross
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117302176