Salmonella Translocated Effectors Recruit OSBP1 to the Phagosome to Promote Vacuolar Membrane Integrity

Summary: Intracellular Salmonella use a type III secretion system (TTSS) to translocate effector proteins across the phagosome membrane and thus promote vacuole membrane tubulation, resulting in intracellular survival. This work demonstrates that the effector SseJ binds the eukaryotic lipid transpor...

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Bibliographic Details
Main Authors: Anna M. Kolodziejek, Melissa A. Altura, Junping Fan, Erik M. Petersen, Matthew Cook, Peter S. Brzovic, Samuel I. Miller
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719304863