The endothelial cell markers von Willebrand Factor (vWF), CD31 and CD34 are lost in glomerulonephritis and no longer correlate with the morphological indices of glomerular sclerosis, interstitial fibrosis, activity and chronicity.

Endothelial cells (ECs) are active participants of an inflammatory process in glomeruli. EC damage has been shown to play an important role in the progression of glomerulonephritis (GN). The degree of glomerular and peritubular capillary loss in models of progressive renal disease correlates with th...

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Main Authors: Flaviu Bob, Gheorghe Bozdog, Silvia Velciov, Ligia Petrica, Virginia Trandafirescu, Diana Herman, Elena Potencz, Gheorghe Gluhovschi, Cristina Gluhovschi, Corina Vernic, Daniel Cioca
Format: Article
Language:English
Published: Via Medica 2010-08-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4237