The Reactions of H<sub>2</sub>O<sub>2</sub> and GSNO with the Zinc Finger Motif of XPA. Not A Regulatory Mechanism, But No Synergy with Cadmium Toxicity

The Reactions of H<sub>2</sub>O<sub>2</sub> and GSNO with the Zinc Finger Motif of XPA. Not A Regulatory Mechanism, But No Synergy with Cadmium Toxicity

Tetrathiolate zinc fingers are potential targets of oxidative assault under cellular stress conditions. We used the synthetic 37-residue peptide representing the tetrathiolate zinc finger domain of the DNA repair protein XPA, acetyl-DYVICEECGKEFMSYLMNHFDLPTCDNCRDADDKHK-amide (XPAzf) as a working mod...

Full description

Bibliographic Details
Main Authors:	Aleksandra Witkiewicz-Kucharczyk, Wojciech Goch, Jacek Olędzki, Andrea Hartwig, Wojciech Bal
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	Molecules
Subjects:	zinc fingers zinc cadmium hydrogen peroxide S-nitrosoglutathione oxidation
Online Access:	https://www.mdpi.com/1420-3049/25/18/4177

Similar Items

Current overview of S-nitrosoglutathione (GSNO) in higher plants
by: Francisco Javier Corpas, et al.
Published: (2013-05-01)

Influence of Zn<sup>+2</sup> Doping on Ni-Based Nanoferrites; (Ni<sub>1−x</sub> Zn<sub>x</sub>Fe<sub>2</sub>O<sub>4</sub>)
by: Sadaf Bashir Khan, et al.
Published: (2019-07-01)

Experimental Study on Influence of Al<sub>2</sub>O<sub>3</sub>, CaO and SiO<sub>2</sub> on Preparation of Zinc Ferrite
by: Jinlin Yang, et al.
Published: (2021-04-01)

Synthesis, magnetic and optical properties of core/shell Co<sub>1-<it>x</it> </sub>Zn<it> <sub>x</sub> </it>Fe<sub>2</sub>O<sub>4</sub>/SiO<sub>2 </sub>nanoparticles
by: Wahsh Mohamed, et al.
Published: (2011-01-01)

Leaching Kinetics of Secondary Zinc Oxide in a NH<sub>3</sub>–NH<sub>4</sub>HCO<sub>3</sub>–H<sub>2</sub>O System
by: Hui Li, et al.
Published: (2021-04-01)

Zinc-Binding Cysteines: Diverse Functions and Structural Motifs
by: Nicholas J. Pace, et al.
Published: (2014-04-01)

On the New Oxyarsenides Eu<sub>5</sub>Zn<sub>2</sub>As<sub>5</sub>O and Eu<sub>5</sub>Cd<sub>2</sub>As<sub>5</sub>O
by: Gregory M. Darone, et al.
Published: (2020-06-01)

Synthesis of Mesoporous Zn<sub>1−x</sub>M<sub>x</sub>Al<sub>2</sub>O<sub>4</sub> Substituted by Co<sup>2+</sup> and Ni<sup>2+</sup> Ions and Application in the Photodegradation of Rhodamine B
by: Nilson Machado Pontes do Nascimento, et al.
Published: (2020-05-01)

Preparation and electrochemical properties of ZnCo<sub>2</sub>O<sub>4</sub> and ZnCo<sub>2</sub>O<sub>4</sub>/rGO composites
by: LI Qin, et al.
Published: (2019-04-01)

Expanding the Repertoire of Target Sites for Zinc Finger Nuclease-mediated Genome Modification
by: Kimberly A Wilson, et al.
Published: (2013-01-01)

Excitons into one-axis crystals of zinc phosphide (Zn<sub>3</sub>P<sub>2</sub>)
by: D.M. Stepanchikov, et al.
Published: (2009-01-01)

The Electrochemical Reduction Mechanism of ZnFe<sub>2</sub>O<sub>4</sub> in NaCl-CaCl<sub>2</sub> Melts
by: Chang Liu, et al.
Published: (2021-08-01)

Where Are the tpy Embraces in [Zn{4′-(EtO)<sub>2</sub>OPC<sub>6</sub>H<sub>4</sub>tpy}<sub>2</sub>][CF<sub>3</sub>SO<sub>3</sub>]<sub>2</sub>?
by: Davood Zare, et al.
Published: (2018-12-01)

Effect of Silica Embedding on the Structure, Morphology and Magnetic Behavior of (Zn<sub>0.6</sub>Mn<sub>0.4</sub>Fe<sub>2</sub>O<sub>4</sub>)<sub>δ</sub>/(SiO<sub>2</sub>)<sub>(100−δ)</sub> Nanoparticles
by: Thomas Dippong, et al.
Published: (2021-08-01)

The Improvement of Coralline-Like ZnGa<sub>2</sub>O<sub>4</sub> by Cocatalysts for the Photocatalytic Degradation of Rhodamine B
by: Jia Yang, et al.
Published: (2020-02-01)

Examination of Various Metal Ion Sources for Reducing Nonspecific Zinc finger−Zn2+ Complex Formation in ESI Mass Spectrometry
by: Soojin Park, et al.
Published: (2012-09-01)

Zinc Metalloproteins in Epigenetics and Their Crosstalk
by: Abdurrahman Pharmacy Yusuf, et al.
Published: (2021-02-01)

Design and Catalytic Behaviour of Hosted in Activated Carbon Foam Co<sub>x</sub>Zn<sub>1−x</sub>Fe<sub>2</sub>O<sub>4</sub> Ferrites
by: Tanya Tsoncheva, et al.
Published: (2021-08-01)

Osteoimmune Modulation and Guided Osteogenesis Promoted by Barrier Membranes Incorporated with S-Nitrosoglutathione (GSNO) and Mesenchymal Stem Cell-Derived Exosomes
by: Wang X, et al.
Published: (2020-05-01)

Hexaborate(2−) and Dodecaborate(6−) Anions as Ligands to Zinc(II) Centres: Self-Assembly and Single-Crystal XRD Characterization of [Zn{κ<sup>3</sup><i>O</i>-B<sub>6</sub>O<sub>7</sub>(OH)<sub>6</sub>}(κ<sup>3</sup><i>N</i>-dien)]·0.5H<sub>2</sub>O (dien = NH(CH<sub>2</sub>–CH<sub>2</sub>NH<sub>2</sub>)<sub>2</sub>), (NH<sub>4</sub>)<sub>2</sub>[Zn{κ<sup>2</sup><i>O</i>-B<sub>6</sub>O<sub>7</sub>(OH)<sub>6</sub>}<sub>2</sub> (H<sub>2</sub>O)<sub>2</sub>]·2H<sub>2</sub>O and (1,3-pnH<sub>2</sub>)<sub>3</sub>[(κ<sup>1</sup><i>N</i>-H<sub>3</sub>N{CH<sub>2</sub>}<sub>3</sub>NH<sub>2</sub>) Zn{κ<sup>3</sup><i>O</i>-B<sub>12</sub>O<sub>18</sub>(OH)<sub>6</sub>}]<sub>2</sub>·14H<sub>2</sub>O (1,3-pn = 1,3-diaminopropane)
by: Mohammed A. Altahan, et al.
Published: (2019-03-01)

Human Cystathionine γ-Lyase Is Inhibited by <i>s</i>-Nitrosation: A New Crosstalk Mechanism between NO and H<sub>2</sub>S
by: Dalila G. F. Fernandes, et al.
Published: (2021-08-01)

Zn/Ni and Zn/Pd Heterobimetallic Coordination Polymers with [SSC-N(CH<sub>2</sub>COO)<sub>2</sub>]<sup>3−</sup> Ligands
by: Phil Liebing, et al.
Published: (2020-06-01)

Genome-wide analysis and stress-responsive expression of CCCH zinc finger family genes in Brassica rapa
by: Boyi Pi, et al.
Published: (2018-12-01)

Solid-Phase “Self-Hydrolysis” of [Zn(NH<sub>3</sub>)<sub>4</sub>MoO<sub>4</sub>@2H<sub>2</sub>O] Involving Enclathrated Water—An Easy Route to a Layered Basic Ammonium Zinc Molybdate Coordination Polymer
by: Kende Attila Béres, et al.
Published: (2021-06-01)

Progress on V<sub>2</sub>O<sub>5</sub> Cathodes for Multivalent Aqueous Batteries
by: Emmanuel Karapidakis, et al.
Published: (2021-04-01)

<it>C. elegans</it> PAT-9 is a nuclear zinc finger protein critical for the assembly of muscle attachments
by: Liu Qian, et al.
Published: (2012-05-01)

Mesoporous Composite Networks of Linked MnFe<sub>2</sub>O<sub>4</sub> and ZnFe<sub>2</sub>O<sub>4</sub> Nanoparticles as Efficient Photocatalysts for the Reduction of Cr(VI)
by: Euaggelia Skliri, et al.
Published: (2021-02-01)

Photocatalytic Degradation of Tetracycline by ZnO/γ-Fe<sub>2</sub>O<sub>3</sub> Paramagnetic Nanocomposite Material
by: Paola Semeraro, et al.
Published: (2020-07-01)

Enhanced Photocatalytic Activity of Spherical Nd<sup>3+</sup> Substituted ZnFe<sub>2</sub>O<sub>4</sub> Nanoparticles
by: Loan T. T. Nguyen, et al.
Published: (2021-04-01)

Knockout of Myostatin by Zinc-finger Nuclease in Sheep Fibroblasts and Embryos
by: Xuemei Zhang, et al.
Published: (2016-10-01)

Optical Sensing of Molecular Oxygen (O<sub>2</sub>) via Metal Oxide Photoluminescence: A Comparative Study of TiO<sub>2</sub>, SnO<sub>2</sub> and ZnO
by: Ambra Fioravanti, et al.
Published: (2021-06-01)

ZnO Structures with Surface Nanoscale Interfaces Formed by Au, Fe<sub>2</sub>O<sub>3</sub>, or Cu<sub>2</sub>O Modifier Nanoparticles: Characterization and Gas Sensing Properties
by: Milena Tomić, et al.
Published: (2021-06-01)

Titania-Based Hybrid Materials with ZnO, ZrO<sub>2</sub> and MoS<sub>2</sub>: A Review
by: Adam Kubiak, et al.
Published: (2018-11-01)

Hydrometalurgical Recovery of Cu and Zn from a Complex Sulfide Mineral by Fe<sup>3+</sup>/H<sub>2</sub>SO<sub>4</sub> Leaching in the Presence of Carbon-Based Materials
by: María Luisa Álvarez, et al.
Published: (2021-02-01)

Association between Serum Zinc and Calcification Propensity (T<sub>50</sub>) in Patients with Type 2 Diabetes Mellitus and In Vitro Effect of Exogenous Zinc on T<sub>50</sub>
by: Shinya Nakatani, et al.
Published: (2020-09-01)

Binder-Free α-MnO<sub>2</sub> Nanowires on Carbon Cloth as Cathode Material for Zinc-ion Batteries
by: Ryan Dula Corpuz, et al.
Published: (2020-04-01)

Zinc fingers: DNA binding and protein-protein interactions
by: OSCAR LEON, et al.
Published: (2000-01-01)

Myocardial ischemic preconditioning upregulated protein 1(Mipu1):zinc finger protein 667 - a multifunctional KRAB/C2H2 zinc finger protein
by: D. Han, et al.
Published: (2015-01-01)

Two-Step Solvothermal Synthesis of (Zn<sub>0.5</sub>Co<sub>0.5</sub>Fe<sub>2</sub>O<sub>4</sub>/Mn<sub>0.5</sub>Ni<sub>0.5</sub>Fe<sub>2</sub>O<sub>4</sub>)@C-MWCNTs Hybrid with Enhanced Low Frequency Microwave Absorbing Performance
by: Pengfei Yin, et al.
Published: (2019-11-01)

Two 1-D Coordination Polymers Containing Zinc(II) Hexaborates: [Zn(en){B<sub>6</sub>O<sub>7</sub>(OH)<sub>6</sub>}]·2H<sub>2</sub>O (en = 1,2-diaminoethane) and [Zn(pn){B<sub>6</sub>O<sub>7</sub>(OH)<sub>6</sub>}]·1.5H<sub>2</sub>O (pn = 1,2-diaminopropane)
by: Mohammed A. Altahan, et al.
Published: (2018-12-01)

Cannot write session to /tmp/vufind_sessions/sess_kvpclqp5l8ol7774ito672jnou