Surface plasmon resonance analysis shows an IgG-isotype-specific defect in ABO blood group antibody formation in patients with common variable immunodeficiency

Surface plasmon resonance analysis shows an IgG-isotype-specific defect in ABO blood group antibody formation in patients with common variable immunodeficiency

Background: Common variable immunodeficiency (CVID) is the most common clinically severe primary immunodeficiency and comprises a heterogeneous group of patients with recurrent severe bacterial infections due to the failure to produce IgG antibodies after exposure to infectious agents and immunizati...

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Bibliographic Details
Main Authors: Michael Bernhard Fischer, Wendelin eWolfram, Christoph J. Binder, Georg A. Böhmig, Markus eWahrmann, Martha M. Eibl, Hermann Maximilian Wolf
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Immunology
Subjects:
Common Variable Immunodeficiency
B cell subsets
Blood groups
Pneumococcal polysaccharide
isoagglutinins
anti-ABO antibodies
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00211/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00211/full

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