Role for A-type lamins in herpesviral DNA targeting and heterochromatin modulation.

Posttranslational modification of histones is known to regulate chromatin structure and transcriptional activity, and the nuclear lamina is thought to serve as a site for heterochromatin maintenance and transcriptional silencing. In this report, we show that the nuclear lamina can also play a role i...

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Bibliographic Details
Main Authors: Lindsey Silva, Anna Cliffe, Lynne Chang, David M Knipe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2374905?pdf=render