More than causing (epi)genomic instability: emerging physiological implications of transposable element modulation

More than causing (epi)genomic instability: emerging physiological implications of transposable element modulation

Abstract Transposable elements (TEs) initially attracted attention because they comprise a major portion of the genomic sequences in plants and animals. TEs may jump around the genome and disrupt both coding genes as well as regulatory sequences to cause disease. Host cells have therefore evolved va...

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Bibliographic Details
Main Authors: Pu-Sheng Hsu, Shu-Han Yu, Yi-Tzang Tsai, Jen-Yun Chang, Li-Kuang Tsai, Chih-Hung Ye, Ning-Yu Song, Lih-Chiao Yau, Shau-Ping Lin
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Biomedical Science
Subjects:
Transposable elements (TEs)
Functional RNAs
Epigenetics
Enhancers
Differentiation
Evolution
Online Access:https://doi.org/10.1186/s12929-021-00754-2

Internet

https://doi.org/10.1186/s12929-021-00754-2

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