Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model

Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model

Abstract The mechanisms triggering renal inflammation in chronic kidney disease (CKD) are unclear. We performed a detailed analysis of the time course of innate and adaptive immunity activation in the 5/6 renal ablation (Nx) model. Munich-Wistar rats undergoing Nx were studied 15, 60 and 120 days af...

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Bibliographic Details
Main Authors: Camilla Fanelli, Simone C. A. Arias, Flavia G. Machado, Jessica K. Okuma, Denise M. A. C. Malheiros, Hatylas Azevedo, Carlos A. Moreira-Filho, Niels O. S. Camara, Clarice K. Fujihara, Roberto Zatz
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02915-6

Internet

https://doi.org/10.1038/s41598-017-02915-6

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