Dynamic perturbations of the T-cell receptor repertoire in chronic HIV infection and following antiretroviral therapy.

Dynamic perturbations of the T-cell receptor repertoire in chronic HIV infection and following antiretroviral therapy.

HIV infection profoundly affects many parameters of the immune system and ultimately leads to AIDS, yet which factors are most important for determining resistance, pathology and response to antiretroviral treatment – and how best to monitor them – remain unclear. We develop a quantitative high thro...

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Bibliographic Details
Main Authors: James Malcolm Heather, Katharine eBest, Theres eOakes, Eleanor R Gray, Jennifer eRoe, Niclas eThomas, Nir eFriedman, Mahdad eNoursadeghi, Benny eChain
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Immunology
Subjects:
Art
HIV
Sequencing
tcr
T cell
aids
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00644/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00644/full

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