Spotlight on the Transglutaminase 2-Heparan Sulfate Interaction
Heparan sulfate proteoglycans (HSPGs), syndecan-4 (Sdc4) especially, have been suggested as potential partners of transglutaminase-2 (TG2) in kidney and cardiac fibrosis, metastatic cancer, neurodegeneration and coeliac disease. The proposed role for HSPGs in the trafficking of TG2 at the cell surfa...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-01-01
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Series: | Medical Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-3271/7/1/5 |