Disease gene interaction pathways: a potential framework for how disease genes associate by disease-risk modules.

BACKGROUND: Disease genes that interact cooperatively play crucial roles in the process of complex diseases, yet how to analyze and represent their associations is still an open problem. Traditional methods have failed to represent direct biological evidences that disease genes associate with each o...

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Bibliographic Details
Main Authors: Lina Chen, Wan Li, Liangcai Zhang, Hong Wang, Weiming He, Jingxie Tai, Xu Li, Xia Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3167857?pdf=render