Successful isolation of Treponema pallidum strains from patients' cryopreserved ulcer exudate using the rabbit model.

Clinical isolates of Treponema pallidum subspecies pallidum (T. pallidum) would facilitate study of prevalent strains. We describe the first successful rabbit propagation of T. pallidum from cryopreserved ulcer specimens. Fresh ulcer exudates were collected and cryopreserved with consent from syphil...

Full description

Bibliographic Details
Main Authors: Lara E Pereira, Samantha S Katz, Yongcheng Sun, Patrick Mills, Willie Taylor, Patricia Atkins, Charles M Thurlow, Kai-Hua Chi, Damien Danavall, Nicholas Cook, Tamanna Ahmed, Alyssa Debra, Susan Philip, Stephanie Cohen, Kimberly A Workowski, Ellen Kersh, Yetunde Fakile, Cheng Y Chen, Allan Pillay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227769