Development and Characterization of New Species Cross-Reactive Anti-Sialoadhesin Monoclonal Antibodies

Sialoadhesin (Sn) is a surface receptor expressed on a subset of macrophages in steady state conditions. During inflammation and diseases, Sn is highly upregulated on macrophages and blood monocytes. Therefore, therapies using monoclonal antibodies (mAbs) to target Sn-positive (Sn+) cells are a pote...

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Bibliographic Details
Main Authors: Marjorie De Schryver, Hanne Van Gorp, Inge Hoebeke, Bauke De Maeyer, Karen Ooms, Isabel Pintelon, Louis J. Maes, Paul Cos, Hans J. Nauwynck, Peter L. Delputte
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Antibodies
Subjects:
Online Access:http://www.mdpi.com/2073-4468/5/2/7