Chronic mild and acute severe glaucomatous neurodegeneration derived from silicone oil-induced ocular hypertension

Abstract Recently, we established silicone oil-induced ocular hypertension (SOHU) mouse model with significant glaucomatous neurodegeneration. Here we characterize two additional variations of this model that simulate two distinct glaucoma types. The first is a chronic model produced by high frequen...

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Bibliographic Details
Main Authors: Fang Fang, Jie Zhang, Pei Zhuang, Pingting Liu, Liang Li, Haoliang Huang, Hannah C. Webber, Yangfan Xu, Liang Liu, Roopa Dalal, Yang Sun, Yang Hu
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88690-x