Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis

Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis

The abilities to invade surrounding tissues and metastasize to distant organs are the most outstanding features that distinguish malignant from benign tumors. However, the mechanisms preventing the invasion and metastasis of benign tumor cells remain unclear. By using our own rat distant metastasis...

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Bibliographic Details
Main Authors: Saya Ozaki, Akihiro Umakoshi, Hajime Yano, Shota Ohsumi, Yutaro Sumida, Erika Hayase, Eika Usa, Afsana Islam, Mohammed E. Choudhury, Yusuke Nishi, Daisuke Yamashita, Yoshihiro Ohtsuka, Masahiro Nishikawa, Akihiro Inoue, Satoshi Suehiro, Jun Kuwabara, Hideaki Watanabe, Yasutsugu Takada, Yuji Watanabe, Ichiro Nakano, Takeharu Kunieda, Junya Tanaka
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Distant metastasis
Brain tumor
Benign
Malignant
Invasion
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558621000439

Internet

http://www.sciencedirect.com/science/article/pii/S1476558621000439

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