Natural killer cells are crucial for the efficacy of Icon (factor VII/human IgG1 Fc) immunotherapy in human tongue cancer

<p>Abstract</p> <p>Background</p> <p>Icon is a novel, dual neovascular- and cancer cell-targeting immunotherapeutic agent and has shown efficacy in the treatment of cancer, wet form macular degeneration and endometriosis. However, its underlying mechanism remains to be...

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Bibliographic Details
Main Authors: Hu Zhiwei, Li Jing
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/11/49