EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance

EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance

Ephrins are transmembrane proteins involved in cell-cell communication, and implicated in cancer cell growth and progression. Here, the authors show that EphrinB2 expression is reduced in glioma cells both by genetic and epigenetic alterations and under hypoxia, through a HIF1α-mediated direct regul...

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Bibliographic Details
Main Authors: C. Depner, H. zum Buttel, N. Böğürcü, A. M. Cuesta, M. R. Aburto, S. Seidel, F. Finkelmeier, F. Foss, J. Hofmann, K. Kaulich, S. Barbus, M. Segarra, G. Reifenberger, B. K. Garvalov, T. Acker, A. Acker-Palmer
Format: Article
Language:English
Published: Nature Publishing Group 2016-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12329

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https://doi.org/10.1038/ncomms12329

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