HIV-1 Nef breaches placental barrier in rat model.

The vertical transmission of HIV-1 from the mother to fetus is known, but the molecular mechanism regulating this transmission is not fully characterized. The fetus is highly protected by the placenta, which does not permit microbial pathogens to cross the placental barrier. In the present study, a...

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Bibliographic Details
Main Authors: Poonam Singh, Saurabh Kumar Agnihotri, Mahesh Chandra Tewari, Sadan Kumar, Monika Sachdev, Raj Kamal Tripathi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519864?pdf=render