Split-Doa10: a naturally split polytopic eukaryotic membrane protein generated by fission of a nuclear gene.
Large polytopic membrane proteins often derive from duplication and fusion of genes for smaller proteins. The reverse process, splitting of a membrane protein by gene fission, is rare and has been studied mainly with artificially split proteins. Fragments of a split membrane protein may associate an...
Main Authors: | Elisabeth Stuerner, Shigehiro Kuraku, Mark Hochstrasser, Stefan G Kreft |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3464245?pdf=render |
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