Insulin-like growth factor-1-mediated regulation of miR-193a expression promotes the migration and proliferation of c-kit-positive mouse cardiac stem cells

Insulin-like growth factor-1-mediated regulation of miR-193a expression promotes the migration and proliferation of c-kit-positive mouse cardiac stem cells

Abstract Background C-kit-positive cardiac stem cells (CSCs) have been shown to be a promising candidate treatment for myocardial infarction and heart failure. Insulin-like growth factor (IGF)-1 is an anabolic growth hormone that regulates cellular proliferation, differentiation, senescence, and dea...

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Bibliographic Details
Main Authors: Yuning Sun, Rongfeng Xu, Jia Huang, Yuyu Yao, Xiaodong Pan, Zhongpu Chen, Genshan Ma
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Stem Cell Research & Therapy
Subjects:
IGF-1
DNMTs
CSCs
c-kit
migration
proliferation
Online Access:http://link.springer.com/article/10.1186/s13287-017-0762-4

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http://link.springer.com/article/10.1186/s13287-017-0762-4

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