Synthesis of Some Substituted 6-Phenyl Purine Analogues and Their Biological Evaluation as Cytotoxic Agents

Synthesis of Some Substituted 6-Phenyl Purine Analogues and Their Biological Evaluation as Cytotoxic Agents

A series of 6-(4-substituted phenyl)-9-(tetrahydropyran-2-yl)purines 3–9, 6-(4-substituted phenyl)purines 10–16, 9-((4-substituted phenyl)sulfonyl)-6-(4-substituted phenyl)purines 17–32 were prepared and screened initially for their in vitro anticancer activity against selected human cancer cells (l...

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Bibliographic Details
Main Authors: Asligul Kucukdumlu, Meral Tuncbilek, Ebru Bilget Guven, Rengul Cetin Atalay
Format: Article
Language:English
Published: Slovenian Chemical Society 2017-09-01
Series:Acta Chimica Slovenica
Subjects:
Antitumor agents
hepatocellular carcinoma
Heterocycles
Purine derivatives
Structure-activity relationships
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/3419

Internet

https://journals.matheo.si/index.php/ACSi/article/view/3419

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