Computational singular perturbation analysis of brain lactate metabolism.

Lactate in the brain is considered an important fuel and signalling molecule for neuronal activity, especially during neuronal activation. Whether lactate is shuttled from astrocytes to neurons or from neurons to astrocytes leads to the contradictory Astrocyte to Neuron Lactate Shuttle (ANLS) or Neu...

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Bibliographic Details
Main Authors: Dimitris G Patsatzis, Efstathios-Al Tingas, Dimitris A Goussis, S Mani Sarathy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226094