The Role of Alternative Splicing in the Control of Immune Homeostasis and Cellular Differentiation

The Role of Alternative Splicing in the Control of Immune Homeostasis and Cellular Differentiation

Alternative splicing of pre-mRNA helps to enhance the genetic diversity within mammalian cells by increasing the number of protein isoforms that can be generated from one gene product. This provides a great deal of flexibility to the host cell to alter protein function, but when dysregulation in spl...

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Bibliographic Details
Main Authors: Mehmet Yabas, Hannah Elliott, Gerard F. Hoyne
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
B cells
T cells
hnRNP proteins
immune tolerance
pre-mRNA alternative splicing
Online Access:http://www.mdpi.com/1422-0067/17/1/3

Internet

http://www.mdpi.com/1422-0067/17/1/3

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