Origin and evolution of the RIG-I like RNA helicase gene family

<p>Abstract</p> <p>Background</p> <p>The DExD/H domain containing RNA helicases such as retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5) are key cytosolic pattern recognition receptors (PRRs) for detecting nucleotide pathogen...

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Bibliographic Details
Main Authors: Nie Pin, Chang Mingxian, Zou Jun, Secombes Chris J
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/9/85