Flow Cytometry Contributions for the Diagnosis and Immunopathological Characterization of Primary Immunodeficiency Diseases With Immune Dysregulation

Flow Cytometry Contributions for the Diagnosis and Immunopathological Characterization of Primary Immunodeficiency Diseases With Immune Dysregulation

Almost 70 years after establishing the concept of primary immunodeficiency disorders (PIDs), more than 320 monogenic inborn errors of immunity have been identified thanks to the remarkable contribution of high-throughput genetic screening in the last decade. Approximately 40 of these PIDs present wi...

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Bibliographic Details
Main Authors: Otavio Cabral-Marques, Lena F. Schimke, Edgar Borges de Oliveira, Nadia El Khawanky, Rodrigo Nalio Ramos, Basel K. Al-Ramadi, Gesmar Rodrigues Silva Segundo, Hans D. Ochs, Antonio Condino-Neto
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
flow cytometry
diagnosis
primary immunodeficiency diseases
immune dysregulation
mutation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02742/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.02742/full

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