Novel Primary Human Cancer Stem-Like Cell Populations from Non-Small Cell Lung Cancer: Inhibition of Cell Survival by Targeting NF-κB and MYC Signaling

Novel Primary Human Cancer Stem-Like Cell Populations from Non-Small Cell Lung Cancer: Inhibition of Cell Survival by Targeting NF-κB and MYC Signaling

There is growing evidence that cancer stem cells (CSCs), a small subpopulation of self-renewal cancer cells, are responsible for tumor growth, treatment resistance, and cancer relapse and are thus of enormous clinical interest. Here, we aimed to isolate new CSC-like cells derived from human primary...

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Bibliographic Details
Main Authors: Beatrice A. Windmöller, Morris Beshay, Laureen P. Helweg, Clara Flottmann, Miriam Beermann, Christine Förster, Ludwig Wilkens, Johannes F. W. Greiner, Christian Kaltschmidt, Barbara Kaltschmidt
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
cancer stem cell-like cells
squamous cell carcinoma
adenocarcinoma
NSCLC
MYC
NF-κB
Online Access:https://www.mdpi.com/2073-4409/10/5/1024

Internet

https://www.mdpi.com/2073-4409/10/5/1024

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