Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli.

Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli.

Priming and activating immune stimuli have profound effects on macrophages, however, studies generally evaluate stimuli in isolation rather than in combination. In this study we have investigated the effects of pro-inflammatory and anti-inflammatory stimuli either alone or in combination on macropha...

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Bibliographic Details
Main Authors: Kevin M Rattigan, Andrew W Pountain, Clement Regnault, Fiona Achcar, Isabel M Vincent, Carl S Goodyear, Michael P Barrett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5851634?pdf=render

Internet

http://europepmc.org/articles/PMC5851634?pdf=render

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