NPBSS: a new PacBio sequencing simulator for generating the continuous long reads with an empirical model

Abstract Background PacBio sequencing platform offers longer read lengths than the second-generation sequencing technologies. It has revolutionized de novo genome assembly and enabled the automated reconstruction of reference-quality genomes. Due to its extremely wide range of application areas, fas...

Full description

Bibliographic Details
Main Authors: Ze-Gang Wei, Shao-Wu Zhang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2208-0