Chronic Obstructive Pulmonary Disease Is Not Associated with KRAS Mutations in Non-Small Cell Lung Cancer.

Mutations in epithelial growth factor receptor (EGFR), as well as in the EGFR downstream target KRAS are frequently observed in non-small cell lung cancer (NSCLC). Chronic obstructive pulmonary disease (COPD), an independent risk factor for developing NSCLC, is associated with an increased activatio...

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Bibliographic Details
Main Authors: Ali Saber, Anthonie J van der Wekken, Gerald S M A Kerner, Maarten van den Berge, Wim Timens, Ed Schuuring, Arja ter Elst, Anke van den Berg, T Jeroen N Hiltermann, Harry J M Groen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0152317