A SENSITIVE ASSAY FOR NON-SPECIFIC N-METHYLTRANSFERASE ACTIVITY IN RAT TISSUES BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY ELECTROCHEMICAL DETECTION

Phenylethanolamine N-methyltransferase (PNMT) and non-specific N -methyltransferase  (EC 2.1.1.28) catalyze the N-methylation of aromatic amines. PNMT is specific for phenylethanolamines such as noradrenaline (NA). and catalyzes the step in catecholamine biosynthesis, forming adrenaline (AD) from NA...

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Bibliographic Details
Main Authors: Dawan Shimbhu, Kohichi Kojima, Toshiharu Nagatsu
Format: Article
Language:English
Published: Universitas Gadjah Mada 2017-12-01
Series:ASEAN Journal on Science and Technology for Development
Online Access:http://www.ajstd.org/index.php/ajstd/article/view/318