Quercetin Inhibits Colorectal Cancer Cells Induced-Angiogenesis in Both Colorectal Cancer Cell and Endothelial Cell through Downregulation of VEGF-A/VEGFR2

Quercetin Inhibits Colorectal Cancer Cells Induced-Angiogenesis in Both Colorectal Cancer Cell and Endothelial Cell through Downregulation of VEGF-A/VEGFR2

Colorectal cancer (CRC) aggressiveness is caused by cancer angiogenesis which promotes the cancer growth and metastasis associated with poor prognosis and poor survival. The vascular endothelial growth factor-A (VEGF-A) and its receptor (VEGFR-2) form the major signaling pathway in cancer angiogenes...

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Bibliographic Details
Main Authors: Tamonwan Uttarawichien, Chantra Kamnerdnond, Tasanee Inwisai, Prasit Suwannalert, Nathawut Sibmooh, Witchuda Payuhakrit
Format: Article
Language:English
Published: Österreichische Apotheker-Verlagsgesellschaft m. b. H. 2021-05-01
Series:Scientia Pharmaceutica
Subjects:
colorectal cancer
angiogenesis
quercetin
NF-κB
VEGF-A
VEGFR-2
Online Access:https://www.mdpi.com/2218-0532/89/2/23

Internet

https://www.mdpi.com/2218-0532/89/2/23

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