Perspectives of pharmacogenetics approach to personalized tamoxifen therapy

Tamoxifen is a selective modulator of estrogen receptors and is widely used in receptor-a-positive breast cancer treatment. Adjuvant tamoxifen treatment substantially reduces breast cancer relapse and mortality rates. However, high interindividual variability in response is observed. One of the caus...

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Bibliographic Details
Main Authors: M I Savelyeva, A K Ignatova, Yu S Panchenko, I A Urvantseva, I V Poddubnaya
Format: Article
Language:Russian
Published: IP Habib O.N. 2017-06-01
Series:Современная онкология
Subjects:
Online Access:https://modernonco.orscience.ru/1815-1434/article/viewFile/27135/pdf